Article
Identifying Diffuse Glioma Subtypes Based on Pathway Enrichment Evaluation.
Interdisciplinary sciences, computational life sciences - 1 Sept 2024
Feng Qiushi, Dong Zehua, Nie Rongfang, Wang Xiaosheng
Abstract excerpt
Gliomas are highly heterogeneous in molecular, histology, and microenvironment. However, a classification of gliomas by integrating different tumor microenvironment (TME) components remains unexplored. Based on the enrichment scores of 17 pathways involved in immune, stromal, DNA repair, and nervous system signatures in diffuse gliomas, we performed consensus clustering to uncover novel subtypes of gliomas....
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