Article

A disease-associated gene desert orchestrates macrophage inflammatory responses via ETS2

2023-05-07

Abstract excerpt

Increasing global rates of autoimmune and inflammatory disease present a burgeoning threat to human health 1 . This is compounded by the limited efficacy of available treatments 1 and high failure rates during drug development 2 – underscoring an urgent need to better understand disease mechanisms. Here we show how genetics could address this challenge. By investigating an intergenic haplotype on chr21q22, inde...

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Literature Corpus work: e858d359-bd9f-525c-b68b-073df1c14805
DOI: 10.1101/2023.05.05.539522

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