Article

Liver biopsies obtained throughout SIV infection reveal evolving interferon stimulated protein expression within distinct monocyte/macrophage subsets

2025-05-07

Abstract excerpt

<h4> ABSTRACT </h4> Liver dysfunction is more common and more severe among people with HIV than in the general population. Our previous transcriptomic analysis identified an increased hepatic type-1 interferon (IFN-1) response in simian immunodeficiency virus (SIV) infected rhesus macaques, including pronounced upregulation of the IFN-1 stimulated gene product MX1. Here, we interrogated the role of different cel...

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Literature Corpus work: e8363eaa-7aef-5706-8fd7-7e4448d8a29c
DOI: 10.1101/2025.05.01.651668

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