Article

Spatial transcriptomics links hepatocyte-macrophage interactions to viral signatures in seronegative hepatitis

2025-11-11

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Seronegative hepatitis (SNH) is an acute fulminant liver injury which leads to liver failure, requiring urgent transplantation. Its clinical, biochemical, and histological features mimic autoimmune hepatitis (AIH). SNH aetiology and pathogenesis is unknown thus defining triggers and immune pathways is essential for timely diagnosis and effective treatment. <b...

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Literature Corpus work: c58469ba-dc64-5665-9914-b4fe7fdb4941
DOI: 10.21203/rs.3.rs-7971511/v1

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