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Article

Hepatic proinflammatory myeloid phenotypes are a hallmark of Ebola virus Kikwit pathogenesis in rhesus monkeys.

Veterinary pathology - 1 Jul 2023

Tseng Anna E, Carossino Mariano, Gertje Hans P, O'Connell Aoife K, Gummuluru Suryaram, Kolachalama Vijaya B, Balasuriya Udeni B R, Connor John H, Bennett Richard S, Liu David X, Hensley Lisa E, Crossland Nicholas A

Abstract excerpt

The liver is an early systemic target of Ebola virus (EBOV), but characterization beyond routine histopathology and viral antigen distribution is limited. We hypothesized Ebola virus disease (EVD) systemic proinflammatory responses would be reflected in temporally altered liver myeloid phenotypes. We utilized multiplex fluorescent immunohistochemistry (mfIHC), multispectral whole slide imaging, and image analysis...

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PMID: 37170900
DOI: 10.1177/03009858231171906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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