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Monkeypox Virus Transcriptional Profiles and Host Responses in Skin Lesion Swabs Among Individuals With Human Immunodeficiency Virus

10 Jun 2025

Abstract excerpt

BACKGROUND: Mpox disease, caused by the monkeypox virus (MPXV), remains a global health concern with nearly half of all cases occurring among individuals with human immunodeficiency virus (HIV). While recent studies have advanced our understanding of poxvirus pathogenesis, the molecular effects of mpox and HIV coinfection are still poorly understood. This study uses dual RNA sequencing (RNA-seq) to characterize...

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PMID: 40498594
DOI: 10.1093/infdis/jiaf316

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