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Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathway

2023-06-24

Abstract excerpt

Cytokine storms are associated with severe pathological damage and death in some diseases. Excessive activation of M1 macrophages and the subsequent secretion of pro-inflammatory cytokines are a major cause of cytokine storms. Therefore, promoting the polarization of M2 macrophages to restore immune balance is a promising therapeutic strategy for treating cytokine storm syndrome (CSS). This study was aimed at inve...

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Identifiers and source

Literature Corpus work
e8167d69-4541-59f5-9fdf-1cde73c600cb
DOI
10.1101/2023.06.21.546014
Open publication

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Leucine alleviates cytokine storm syndrome by regulating macrophage polarization via the mTORC1/LXRα signaling pathwayDOI 10.1101/2023.06.21.546014
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