Article
Contribution of Macrophage Polarization to Metabolic Diseases.
Journal of atherosclerosis and thrombosis - 1 Jan 2016
Komohara Yoshihiro, Fujiwara Yukio, Ohnishi Koji, Shiraishi Daisuke, Takeya Motohiro
Abstract excerpt
Macrophage activation is one of the major immunological events in the pathogenesis of various diseases. Recent studies have disclosed that complicated mechanisms are involved in macrophage activation and polarization, and many published research articles have been based on the M1/M2 polarization concept. It is considered that M1- and M2-like macrophages are associated with T helper (Th)1-type and Th2-type immune...
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