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Article

The roles of macrophage polarization in the host immune response to sepsis.

International immunopharmacology - 1 Jul 2021

Chen Xinsen, Liu Yancun, Gao Yulei, Shou Songtao, Chai Yanfen

Abstract excerpt

Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is complex and entails coagulation dysfunction, inflammation, and immune disorders. Macrophages are important components of innate and adaptive immunity that are highly heterogeneous and plastic. They can polarize into a multi-dimensional spectrum of phenotypes with different functions relating to immune regulation in response to...

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Identifiers

PMID: 34162154
DOI: 10.1016/j.intimp.2021.107791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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