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Article

A single-cell atlas of the aging murine ovary

2023-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Ovarian aging leads to diminished fertility, dysregulated endocrine signaling, and increased chronic disease burden. These effects begin to emerge long before follicular exhaustion. Around 35 years old, women experience a sharp decline in fertility, corresponding to declines in oocyte quality. Despite a growing body of work, the field lacks a comprehensive cellular map of the transcriptomic chan...

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Literature Corpus work
e80ea4e9-b4de-5d7a-bde4-f2ddc62daa37
DOI
10.1101/2023.04.29.538828
Open publication

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A single-cell atlas of the aging murine ovaryDOI 10.1101/2023.04.29.538828
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