Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A single-cell transcriptomic landscape of mouse testicular aging

14 Dec 2022

Abstract excerpt

INTRODUCTION: Advanced paternal age of reproduction is an increasing trend, especially in developed countries and areas. This trend results in elevated risks of adverse reproductive outcomes such as reduced fertility rates, increased pregnancy loss, and poor childhood health. Yet, a systematic profiling of aging-associated molecular and cellular alterations in testicular tissue is still missing. OBJECTIVES: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunotherapy and Immune Responses
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36528294
DOI: 10.1016/j.jare.2022.12.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A single-cell transcriptomic landscape of mouse testicular agingPMID 36528294Read ↗

A single-cell atlas of the aging mouse ovarySemantic proximity Read ↗

Transcriptome Analysis of Testicular Aging in MiceSemantic proximity Read ↗

Single-cell analysis of human testis aging and correlation with elevated body mass indexSemantic proximity Read ↗

A single-cell atlas of the aging murine ovarySemantic proximity Read ↗

Single-Cell Analysis of Human Testis Aging, and Impact of Elevated Body Mass IndexSemantic proximity Read ↗

A Panoramic View of Cell Population Dynamics in Mammalian AgingSemantic proximity Read ↗

Anatomical Transcriptome Atlas of the Male Mouse Reproductive System During AgingSemantic proximity Read ↗

A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasisSemantic proximity Read ↗

Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cellsSemantic proximity Read ↗

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiationSemantic proximity Read ↗

Multi-Omics Perspectives on Testicular Aging: Unraveling Germline Dysregulation, Niche Dysfunction, and Epigenetic RemodelingSemantic proximity Read ↗

Single-cell transcriptomics identifies senescence-associated secretory phenotype (SASP) features of testicular aging in human.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.