Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell profiling of mouse and primate ovaries identifies high levels of EGFR for stromal cells in ovarian aging

25 Nov 2022

Abstract excerpt

Increased ovarian fibrosis and an expanded stromal cell compartment are the main characteristics of aging ovaries. However, the molecular mechanisms and the key factor of stromal cells underlying ovarian aging remain unclear. Here, we explored single-cell transcriptomic data of ovaries from the adult mouse (4,363 cells), young (1,122 cells), and aged (1,479 cells) non-human primates (NHPs) to identify expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian cancer diagnosis and treatment
Share to Reproductive Biology and Fertility
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36570672
DOI: 10.1016/j.omtn.2022.11.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell profiling of mouse and primate ovaries identifies high levels of EGFR for stromal cells in ovarian agingPMID 36570672Read ↗

A single-cell atlas inclusive of age-related menopause reveals global tissue and ovarian remodelingSemantic proximity Read ↗

A single-cell atlas of the aging murine ovarySemantic proximity Read ↗

A single-cell atlas of the aging mouse ovarySemantic proximity Read ↗

Single-cell RNA sequencing reveals the intercellular crosstalk and the regulatory landscape of stromal cells during the whole life of the mouse ovarySemantic proximity Read ↗

Comparative analysis of human and mouse ovaries across ageSemantic proximity Read ↗

Spatiotemporal analysis of human ovarian aging at single-cell resolutionSemantic proximity Read ↗

Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomicsSemantic proximity Read ↗

Self-organizing ovarian somatic organoids preserve cellular heterogeneity and reveal cellular contributions to ovarian agingSemantic proximity Read ↗

Temporal transcriptomic landscape of postnatal mouse ovaries reveals dynamic gene signatures associated with ovarian agingSemantic proximity Read ↗

Single‐Cell Atlas of Human Ovaries Reveals The Role Of The Pyroptotic Macrophage in Ovarian AgingSemantic proximity Read ↗

Single-cell reconstruction of follicular remodeling in the human adult ovarySemantic proximity Read ↗

Impact of Aging on the Ovarian Extracellular Matrix and Derived 3D ScaffoldsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.