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Aging hallmarks of the primate ovary revealed by spatiotemporal transcriptomics

16 Dec 2023

Abstract excerpt

The ovary is indispensable for female reproduction, and its age-dependent functional decline is the primary cause of infertility. However, the molecular basis of ovarian aging in higher vertebrates remains poorly understood. Herein, we apply spatiotemporal transcriptomics to benchmark architecture organization as well as cellular and molecular determinants in young primate ovaries and compare these to aged...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38126810
DOI: 10.1093/procel/pwad063

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