Article

Mitogen and Stress-Activated Kinases 1 and 2 Mediate Endothelial Dysfunction

2020-12-04

Abstract excerpt

<h4>ABSTRACT</h4> Inflammation promotes endothelial dysfunction. Using translational vascular function testing in myocardial Infarction patients, a situation where inflammation is prevalent, and knock-out (KO) mouse models we demonstrate a role for mitogen-activated-protein-kinases (MAPKs) in endothelial dysfunction. Myocardial infarction significantly lowers mitogen and stress kinase 1/2 (MSK1/2) expression in pe...

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Literature Corpus work: e8093574-929c-5817-a384-ac182382c7b4
DOI: 10.1101/2020.12.03.20243105

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