Article

NR2F2 is required in the embryonic testis for Fetal Leydig Cell development

2024-07-19

Abstract excerpt

Male genital development in XY mammalian fetuses is triggered by the action of hormones, including testosterone, secreted by the developing testes. Defects in this process are a cause for Differences in Sex Development (DSD), one of the most common congenital abnormalities in humans. Fetal Leydig Cells (FLC) play a central role for the synthesis of masculinizing hormones in the developing testes. Yet, the genetic...

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Literature Corpus work: e8063cca-b6c9-5ee7-a1f6-3a2bd559c080
DOI: 10.1101/2024.07.17.602099

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