Article

The mechanosensitive TRPV2 calcium channel controls human melanoma invasiveness and metastatic potential

2021-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Discovery of therapeutic targets against metastasis is of primary importance since being the main cause of cancer-related death. Melanoma is a highly aggressive cancer endowed with a unique capacity of rapidly metastasizing. Deregulation of calcium homeostasis has been involved in numerous cellular metastatic behaviors, although the molecular determinants supporting these processes often remain...

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Literature Corpus work: e7b7cb41-2cb5-5214-970e-36670fbb7c9d
DOI: 10.1101/2021.10.22.465391

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