Article

Mapping and phenotyping genes in the Del(13)Svea36H region of mouse chromosome 13

2009-01-01

Abstract excerpt

Del(13)Svea36H (also known as Del36H) is a 12.7Mb gene-rich region that has been deleted in mouse chromosome 13. It contains numerous disease loci as well as showing conserved synteny to two regions of human chromosome 6p which can be missing in some deletion syndromes. The mouse deletion causes homozygous embryonic lethality but is hemizygously viable. It has therefore been used as a tool to screen for lethal rec...

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Literature Corpus work: e7886db7-f186-5c2e-bbc7-21dd2c5f5de0
DOI: 10.21954/ou.ro.0000f274

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