Article
Genetic, physical, and phenotypic characterization of the Del(13)Svea36H mouse.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 2001
Arkell R M, Cadman M, Marsland T, Southwell A, Thaung C, Davies J R, Clay T, Beechey C V, Evans E P, Strivens M A, Brown S D, Denny P
Abstract excerpt
The Del(13)Svea36H deletion was recovered from a radiation mutagenesis experiment and represents a valuable resource for investigating gene content and function at this region of mouse Chromosome (Chr) 13 and human Chr 6p21.3-23 and 6p25. In this paper we examine the physical extent of chromosome loss and construct an integrated genetic and radiation hybrid map of the deleted segment. We show that embryos which...
Topics
- Animals
- Chromosome Deletion
- Chromosomes
- Cricetinae
- Cytogenetic Analysis
- DNA Primers
- Genetic Markers
- Genotype
- Homozygote
- Mice
- Mice, Inbred C3H