Article
Physical delineation of a 700-kb region overlapping the Looptail mutation on mouse chromosome 1.
Genomics - 15 Jan 1999
Underhill D A, Mullick A, Groulx N, Beatty B G, Gros P
Abstract excerpt
The mouse looptail (Lp) mutation is an established model for neural tube defects with homozygous Lp embryos showing an open neural tube from the caudal midbrain to the tip of the tail. Heterozygous Lp mice are characterized by a "looped-tail" and wobbly head movements. The Lp gene has been mapped to a 0.6-cM interval on mouse chromosome 1 delineated by two clusters of markers, Fcer1gamma/Usf1/D1Mit113/D1Wsu1 on...
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