Article
Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse.
The Journal of heredity - 1 Jan 2000
Sweet H O, Bronson R T, Donahue L R, Davisson M T
Abstract excerpt
Mesenchymal dysplasia (mes) is a new autosomal recessive mouse mutation that alters normal growth of mesenchyme-derived tissues and provides a new mouse model for studying connective tissue development and defects. Mutants are characterized by preaxial polydactyly of all four feet, a shortened fa...
Topics
- Abnormalities, Multiple
- Animals
- Body Composition
- Chromosome Mapping
- Female
- Genes, Recessive
- Insulin-Like Growth Factor Binding Proteins
- Insulin-Like Growth Factor I
- Male
- Mesoderm
- Mice
- Mice, Inbred CBA
- Mutation
- Reproduction
