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Article

Lipid-induced conformational transition of the amyloid core fragment Abeta(28-35) and its A30G and A30I mutants.

The FEBS journal - 1 May 2008

Nagarajan Sureshbabu, Ramalingam Kirubagaran, Neelakanta Reddy P, Cereghetti Damiano M, Padma Malar E J, Rajadas Jayakumar

Abstract excerpt

The interaction of the beta-amyloid peptide (Abeta) with neuronal membranes could play a key role in the pathogenesis of Alzheimer's disease. Recent studies have focused on the interactions of Abeta oligomers to explain the neuronal toxicity accompanying Alzheimer's disease. In our study, we have investigated the role of lipid interactions with soluble Abeta(28-35) (wild-type) and its mutants A30G and A30I in...

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PMID: 18422968
DOI: 10.1111/j.1742-4658.2008.06378.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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