Article

Metabolic specialization drives reduced pathogenicity in <i>Pseudomonas aeruginosa</i> CF clinical isolates

2023-04-17

Abstract excerpt

Metabolism provides the foundation for all cellular functions. During persistent infections, in adapted pathogenic bacteria metabolism functions radically differently compared with more naïve strains. Whether this is simply a necessary accommodation to the persistence phenotype or if metabolism plays a direct role in achieving persistence in the host is still unclear. Here, we characterize a convergent shift in me...

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Literature Corpus work: e7405b9d-7de5-57a5-a068-dfe54b73fcdf
DOI: 10.1101/2023.04.17.537125

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