Back to search

Article

Long-term adaptation to hypoxia provides insight into mechanisms facilitating the switch of <i>Pseudomonas aeruginosa</i> to chronic lung infections

2024-12-26

Abstract excerpt

Opportunistic bacterial infections are an increasing threat, especially for immunocompromised individuals such as people with cystic fibrosis (CF), driving morbidity and mortality. Pseudomonas aeruginosa is a key pathogen associated with chronic lung infections, that has been extensively studied in this context, but the mechanism(s) driving its adaptation towards chronic colonisation in the lung are not fully und...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
acc15728-8e52-509c-9004-49d5e777053c
DOI
10.1101/2024.12.26.630387
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Long-term adaptation to hypoxia provides insight into mechanisms facilitating the switch of <i>Pseudomonas aeruginosa</i> to chronic lung infectionsDOI 10.1101/2024.12.26.630387
Pseudomonas aeruginosa infection and persistence mechanisms in cystic fibrosis patientsSemantic proximity
From genotype to phenotype: adaptations of Pseudomonas aeruginosa to the cystic fibrosis environment.Semantic proximity
The nutritional environment is sufficient to select coexisting biofilm and quorum-sensing mutants of <i>Pseudomonas aeruginosa</i>Semantic proximity
Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A ReviewSemantic proximity
How long does it take to cue a <i>Pseudomonas aeruginosa</i> chronic infection phenotype in the lab? Insights from transcriptome analysis in a cystic fibrosis lung modelSemantic proximity
Contribution of Oxygen-Limiting Conditions to Persistent Infection of<i>Pseudomonas Aeruginosa</i>Semantic proximity
Chronic <i>Staphylococcus aureus</i> lung infection correlates with proteogenomic and metabolic adaptations leading to an increased intracellular persistenceSemantic proximity
Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis LungsSemantic proximity
Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary diseaseSemantic proximity
Adaptive evolution of <i>P. aeruginosa</i> in human airways shows phenotypic convergence despite diverse patterns of genomic changesSemantic proximity
Multi-omics profiling reveals convergent adaptation of urinary <i>Pseudomonas aeruginosa</i> isolatesSemantic proximity
Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence FactorsSemantic proximity
Select a neighboring publication to make it the new centre.