Article
Cell Specific Reactivation of Epicardium at the Origin of Fibro-Fatty Remodeling of the Atrial Myocardium
2019-03-28
Abstract excerpt
<h4> Abstract </h4> Epicardium, the mesothelium covering the heart, is composed of multipotent cells and is reactivated following myocardial injury in adults. Herein, we provide evidence for activation of atrial epicardium in aged patients with diseased atria and in murine models of atrial remodeling. Epicardial activation contributed to fibro-fatty infiltration of sub-epicardium that contained a number of cells...
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Identifiers and source
- Literature Corpus work
- e732ca44-b08d-534c-8abe-4cdabf648d42
- DOI
- 10.1101/589705