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Chemo- versus immuno-precipitation of G-quadruplex-DNA (G4DNA): a direct comparison of the efficiency of the antibody BG4 versus the small-molecule ligands TASQs for G4 affinity capture

2022-06-15

Abstract excerpt

<title>Abstract</title> <p>The search for genomic G-quadruplex (G4) motifs is motivated by their involvement in key cellular processes ( e.g ., transcription, replication) and corresponding dysregulations underlying genetic diseases. Sequencing-based methods have been developed to assess G4 DNA formation genome-wide, including G4-seq that detects G4s in purified DNA (so called in vitro ) from human lymphocytes us...

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Literature Corpus work: e72bbb4f-5965-5ac2-a87f-9b211478cc15
DOI: 10.21203/rs.3.rs-1717207/v1

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Chemo- versus immuno-precipitation of G-quadruplex-DNA (G4DNA): a direct comparison of the efficiency of the antibody BG4 versus the small-molecule ligands TASQs for G4 affinity captureDOI 10.21203/rs.3.rs-1717207/v1Read

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