Distinct RET Fusion Partner Genes in RET-Rearranged Spindle Cell Tumors Contribute to Varied Transformation Capacities

Abstract excerpt

<title>Abstract</title> <p><italic>RET</italic>-rearranged spindle cell tumors represent a group of soft tissue tumors with heterogeneous clinical presentations. While some tumors are benign, others display malignant behavior with metastatic potential. The underlying causes of this heterogeneity are unknown but are suspected to be associated with the diverse fusion partner genes involved in <italic>RET</italic> r...

Topics

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• Benzoquinones
• Gene Fusion
• Mutation
• Neurofibromatosis and Schwannoma Cases
• Sarcoma Diagnosis and Treatment
• Soft Tissue Neoplasms
• Uterine Myomas and Treatments
• Vascular Tumors and Angiosarcomas

Identifiers and source

Literature Corpus work

e6f7b3a6-8add-59c2-84ac-42f334e8e220

DOI

10.21203/rs.3.rs-6513808/v1