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NTRK Fusions in a Sarcomas Series: Pathology, Molecular and Clinical Aspects

11 May 2022

Abstract excerpt

Targeting molecular alterations has been proven to be an inflecting point in tumor treatment. Especially in recent years, inhibitors that target the tyrosine receptor kinase show excellent response rates and durable effects in all kind of tumors that harbor fusions of one of the three neurotrophic tyrosine receptor kinase genes (NTRK1, NTRK2 and NTRK3). Today, the therapeutic options in most metastatic sarcomas...

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PMID: 35645621
DOI: 10.3389/pore.2022.1610423

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