Article

Dissecting PTEN function in cancer

2017-01-01

Abstract excerpt

PTEN downregulates a number of essential biological processes such as cell proliferation, survival and growth. Alterations of PTEN levels can lead to cancer, and PTEN is indeed one of the most frequently disrupted tumour suppressor genes in human cancers. Thus, anti-cancer treatment strategies focusing on PTEN deficiency could prove very beneficial. As such, a wide range of therapeutic approaches targeting cancers...

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Literature Corpus work: e64c67ef-4cd7-5a83-af66-86a6c2511c39
DOI: 10.25560/68504

Open publication

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