Article

AAV Capsid Chimeras with Enhanced Infectivity reveal a core element in the AAV Genome critical for both Cell Transduction and Capsid Assembly

2020-10-13

Abstract excerpt

<h4>ABSTRACT</h4> Adeno-associated viruses (AAV) have attracted significant attention in the field of gene and cell therapy due to highly effective delivery of therapeutic genes into human cells. The ability to generate recombinant AAV vectors compromised of unique or substituted protein sequences has led to the development of capsid variants with improved therapeutic properties. Seeking a novel AAV capable of en...

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Literature Corpus work: e63831f7-0840-5ea2-98aa-c866a4b3a6f0
DOI: 10.1101/2020.10.13.337261

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AAV Capsid Chimeras with Enhanced Infectivity reveal a core element in the AAV Genome critical for both Cell Transduction and Capsid AssemblyDOI 10.1101/2020.10.13.337261Read

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