Article
Machine learning-based definition of cellular senescence reveals pro-senescence potential implication in lung adenocarcinoma
2025-10-13
Abstract excerpt
Despite growing evidence implicating cellular senescence in tumor progression, methodological challenges in objectively quantifying senescent cell burden across cancer types continue to limit mechanistic studies and clinical translation. To address this, we developed the Predictive Cellular Senescence Model (PreCSenM), a machine learning-based tool that assigns a CS score by integrating senescence-associated featu...
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Identifiers and source
- Literature Corpus work
- 8957078b-0e68-51b4-8e5e-aa12741f9383
- DOI
- 10.1101/2025.10.11.681821