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Deep Learning Shows Cellular Senescence Is a Barrier to Cancer Development

2021-03-19

Abstract excerpt

Cellular senescence is a critical component of aging and many age-related diseases, but understanding its role in human health is challenging in part due to the lack of exclusive or universal markers. Using neural networks, we achieve high accuracy in predicting senescence state and type from the nuclear morphology of DAPI-stained human fibroblasts, murine astrocytes and fibroblasts derived from premature aging di...

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Literature Corpus work: 59241b63-f7e2-5f8d-811f-e287b12e0e81
DOI: 10.1101/2021.03.18.435987

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