Article

miniMTI: minimal multiplex tissue imaging enhances biomarker expression prediction from histology

2026-03-19

Abstract excerpt

<title>Abstract</title> <p>Virtual multiplexing from routine histology has advanced rapidly, yet morphology alone provides limited access to molecular state, imposing an intrinsic ceiling on H&E-only inference. Here, we introduce miniMTI, a molecularly anchored virtual staining framework that determines the minimal set of experimentally measured markers required, alongside H&E, to accurately reconstruct large mul...

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Literature Corpus work: e5cd3e30-0d70-50e0-9b35-6f7806197bec
DOI: 10.21203/rs.3.rs-8865586/v1

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