Article

Inference of single cell profiles from histology stains with the Single Cell omics from Histology Analysis Framework (SCHAF)

2023-03-23

Abstract excerpt

Tissue biology involves an intricate balance between cell-intrinsic processes and interactions between cells organized in specific spatial patterns, which can be respectively captured by single cell profiling methods, such as single cell RNA-seq (scRNA-seq) and spatial transcriptomics, and histology imaging data, such as Hematoxylin-and-Eosin (H&E) stains. While single cell profiles provide rich molecular informat...

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Literature Corpus work: 73f2a252-2596-57a8-b4ca-1f2de0f2a61f
DOI: 10.1101/2023.03.21.533680

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