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Article

Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementias.

Nature genetics - 1 Jun 2026

Abstract excerpt

To better characterize the genetic architecture underlying Alzheimer's disease (AD) and related dementias (ADRD), we performed a meta-analysis of European-ancestry genome-wide association studies in 128,681 cases or proxy cases of ADRD and 849,833 (proxy) controls. We identified 91 genetic loci associated with ADRD risk, of which 16 are new and 56 are specifically detected in clinically diagnosed AD cases. We...

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Source

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Identifiers

PMID: 42237039
DOI: 10.1038/s41588-026-02583-1
PMCID: PMC13263136

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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