Article

NUAK1 regulates contraction in vascular smooth muscle cells derived from abdominal aortic aneurysm patients

2024-12-20

Abstract excerpt

<h4>Aim</h4> Abdominal aortic aneurysms (AAA) are defined as a dilatation of the aortic wall. Impaired contractile ability of vascular smooth muscle cells (vSMC) is a hallmark of AAA. This study investigates the underlying mechanism of altered in vitro contractility of vSMC derived from AAA patients (AAA-SMC) compared to control vSMC (C-SMC). <h4>Methods</h4> Contractility of AAA-SMC (n=24) and C-SMC (n=8) was...

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Literature Corpus work: e5b56d41-3e08-584c-93f9-92cfd9d35590
DOI: 10.1101/2024.12.19.629332

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