Article

A CRISPR-Cas9-mediated F0 screen to identify pro-regenerative genes in the zebrafish retinal pigment epithelium

2022-08-29

Abstract excerpt

<h4>ABSTRACT</h4> Ocular diseases resulting in death of the retinal pigment epithelium (RPE) lead to vision loss and blindness. There are currently no FDA-approved strategies to restore damaged RPE cells. Stimulating intrinsic regenerative responses within damaged tissues has gained traction as a possible mechanism for tissue repair. Zebrafish possess remarkable regenerative abilities, including within the RPE; h...

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Literature Corpus work: d4e90f8b-b3e8-59f3-a7bf-cc5a7f98bf26
DOI: 10.1101/2022.08.28.505611

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