Article

Molecular regulation of retinal regeneration is context specific

2023-11-21

Abstract excerpt

Many genes are known to regulate retinal regeneration following widespread tissue damage. Conversely, genes controlling regeneration following limited retinal cell loss, akin to disease conditions, are undefined. Combining a novel retinal ganglion cell (RGC) ablation-based glaucoma model, single cell omics, and rapid CRISPR/Cas9-based knockout methods to screen 100 genes, we identified 18 effectors of RGC regenera...

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Literature Corpus work: dd5f1749-e23b-564c-b331-d61179bdaafd
DOI: 10.1101/2023.11.20.567904

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