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The Role of Histone Deacetylases in Acute Lung Injury—Friend or Foe

26 Apr 2023

Abstract excerpt

Acute lung injury (ALI), caused by intrapulmonary or extrapulmonary factors such as pneumonia, shock, and sepsis, eventually disrupts the alveolar-capillary barrier, resulting in diffuse pulmonary oedema and microatasis, manifested by refractory hypoxemia, and respiratory distress. Not only is ALI highly lethal, but even if a patient survives, there are also multiple sequelae. Currently, there is no better...

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PMID: 37175583
DOI: 10.3390/ijms24097876

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