Article

Human <i>VDAC</i> pseudogenes: an emerging role for <i>VDAC1P8</i> pseudogene in acute myeloid leukemia

2023-01-21

Abstract excerpt

<h4>Background</h4> Voltage-dependent anion selective channels (VDACs) are the most abundant mitochondrial outer membrane proteins, encoded in mammals by three genes, VDAC1 , 2 and 3 , mostly ubiquitously expressed. As ‘mitochondrial gatekeepers’, VDACs control organelle and cell metabolism and are involved in many diseases. Despite the presence of numerous VDAC pseudogenes in the human genome, their signifi...

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Literature Corpus work: e564a158-44ad-5149-88ce-fba9472aec45
DOI: 10.1101/2023.01.20.524880

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