Article

High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma

2023-07-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Primary open angle glaucoma (POAG) is a leading cause of blindness globally. Characterised by progressive retinal ganglion cell degeneration, the precise pathogenesis remains unknown. Genome-wide association studies (GWAS) have uncovered many genetic variants associated with elevated intraocular pressure (IOP), one of the key risk factors for POAG. This study sought to inv...

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Literature Corpus work: e4fe65a9-709d-5c29-9958-78467cbf4c0e
DOI: 10.1101/2023.07.10.548340

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