Article

Retinal ganglion cell-specific genetic regulation in primary open angle glaucoma

2021-07-14

Abstract excerpt

<h4>ABSTRACT</h4> To assess the transcriptomic profile of disease-specific cell populations, fibroblasts from patients with primary open-angle glaucoma (POAG) were reprogrammed into induced pluripotent stem cells (iPSCs) before being differentiated into retinal organoids and compared to those from healthy individuals. We performed single-cell RNA-sequencing of a total of 330,569 cells and identified cluster-speci...

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Literature Corpus work: 6c58cc3b-3351-5818-b267-fd57e19bbac1
DOI: 10.1101/2021.07.14.452417

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