Article

eIF3 interactions with miRNAs involved in translational control of early T cell activation

2026-06-19

Abstract excerpt

Early T cell activation induces extensive remodeling of the cellular transcriptome and proteome. We previously showed using a transcriptome-wide crosslinking approach that human translation initiation factor eIF3 directly interacts with a select set of immune-related mRNAs shortly after T cell activation. We also found that eIF3 binding to the 3′-untranslated regions (3′-UTRs) of the TCRA and TCRB mRNAs encoding...

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Literature Corpus work: e4f2901e-42df-5379-89aa-e56c75bedf7a
DOI: 10.64898/2026.06.17.732961

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