Article

Comprehensive Analysis of TP53 Mutation Characteristics and Identification of Patients with Inferior Prognosis and Enhanced Immune Escape in Diffuse Large B Cell Lymphoma

2021-07-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous lymphatic malignancy. The role of <italic>TP53</italic> gene alterations in DLBCL remains unclear. <bold>Methods:</bold> We performed a comprehensive analysis of the genomic characteristics of <italic>TP53</italic> through targeted next-generation sequencing (n=176), RNA-sequencing (n=152), and circ...

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Literature Corpus work: e4ec5c39-9c9c-56c6-9514-cf4dc198000b
DOI: 10.21203/rs.3.rs-724635/v1

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