Article

Prognostic Analysis of Diffuse Large B-Cell Lymphoma Patients Based on Clinical Characteristics, TP53 Mutation Status, and Number of Co-mutated Genes

2025-06-25

Abstract excerpt

<title>Abstract</title> <p>We retrospectively analyzed 59 patients newly diagnosed with diffuse large B-cell lymphoma (DLBCL) in our hospital, based on next-generation sequencing mutation analysis and clinical characteristics. One or more mutations were detected in all patients, with a median mutation count of four (range 1–9). The genes with the highest mutation frequencies (> 10%) included TP53 (37.3%), KMT2D (...

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Literature Corpus work: 05f87a17-6ed7-55c3-a3a5-c66f0dbc89c0
DOI: 10.21203/rs.3.rs-6665588/v1

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