Association of the G‐2548A polymorphism in the 5′ region of the <i>LEP</i> gene with overweight

Abstract excerpt

Mutations in the translated part of the leptin gene ( LEP ) have been found in only two families. Nevertheless DNA polymorphisms in the LEP region are linked to extreme obesity. We previously found in the 5′ region of LEP a polymorphism, G‐2548A, associated with a difference in BMI reduction following a low calorie diet in overweight women. Recently, this polymorphism was associated with extreme obesity in women....

Topics

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• Adipokines, Inflammation, and Metabolic Diseases
• Biochemical Analysis and Sensing Techniques
• Regulation of Appetite and Obesity

Identifiers and source

Literature Corpus work

e412757b-06ae-5b68-bfd8-5738369a754f

DOI

10.1046/j.1469-1809.2000.6450391.x