Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leptin G-2548A promoter polymorphism is associated with increased plasma leptin and BMI in Brazilian women.

Arquivos brasileiros de endocrinologia e metabologia - 1 Jun 2008

Hinuy Hamilton M, Hirata Mario H, Forti Neusa, Diament Jayme, Sampaio Marcelo F, Armaganijan Dikran, Salazar Luis A, Hirata Rosario D C

Abstract excerpt

Variants in leptin gene (LEP) have been implicated in the pathogenesis of obesity. The relationship between LEP G-2548A polymorphism and obesity-related traits was evaluated in a sample of Brazilian women (n = 228) who were randomly selected from two clinical centers in Sao Paulo city. Blood samples were collected for DNA extraction, plasma leptin and serum lipids measurements. LEP G-2548A genotypes were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Brazil

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Leptin

Share to Obesity

Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 18604373
DOI: 10.1590/s0004-27302008000400006

Genes

LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leptin G-2548A promoter polymorphism is associated with increased plasma leptin and BMI in Brazilian women.PMID 18604373Read ↗

Association with leptin gene C.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients.Semantic proximity Read ↗

LEP -2548G>A Polymorphism of the Leptin Gene and Its Influence on the Lipid Profile in Obese Individuals.Semantic proximity Read ↗

Leptin promoter variant G2548A is associated with serum leptin and HDL-C levels in a case control observational study in association with obesity in a Pakistani cohort.Semantic proximity Read ↗

Influence of the leptin G-2548A polymorphism on leptin levels and anthropometric measurements in healthy Spanish adolescents.Semantic proximity Read ↗

Leptin gene G-2548A polymorphism in Iranian subjects with metabolic syndrome.Semantic proximity Read ↗

Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight.Semantic proximity Read ↗

Association of leptin gene -2548 G/A polymorphism with obesity: a meta-analysis.Semantic proximity Read ↗

[Association of leptin gene-2548 G/A polymorphism with obesity: a meta-analysis].Semantic proximity Read ↗

Leptin G-2548A Gene Polymorphism is Positively Associated with Increased Plasma Leptin and Glucose Levels in Obese Saudi Patients Irrespective Status of Blood Pressure    Semantic proximity Read ↗

The -2548G/A LEP polymorphism is associated with blood pressure in Tunisian obese patients.Semantic proximity Read ↗

Association of G-2548A LEP polymorphism with plasma leptin levels in Tunisian obese patientsSemantic proximity Read ↗

Role of leptin G-2548A polymorphism in age- and gender-specific development of obesity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.