Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of leptin gene -2548 G/A polymorphism with obesity: a meta-analysis.

Annals of nutrition & metabolism - 1 Jan 2014

Zhang Ling, Yuan Lin-Hong, Xiao Yun, Lu Ming-yang, Zhang Li-jing, Wang Yin

Abstract excerpt

BACKGROUND: A common single-nucleotide polymorphism identified in the 5'-untranslated region of the leptin gene (LEP -2548 G/A polymorphism) may be associated with obesity, but the existing research findings are inconsistent, so we conducted this meta-analysis. METHODS: Medline, Embase and ISI Web of Science databases were searched to identify relevant studies. Meta-analysis of the total and subgroup populations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Databases, Factual
Share to Ethnicity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Leptin

Share to Obesity

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 25034151
DOI: 10.1159/000363392

Genes

LEP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of leptin gene -2548 G/A polymorphism with obesity: a meta-analysis.PMID 25034151Read ↗

[Association of leptin gene-2548 G/A polymorphism with obesity: a meta-analysis].Semantic proximity Read ↗

Lack of association between leptin G-2548A polymorphisms and obesity risk: Evidence based on a meta-analysis.Semantic proximity Read ↗

Association with leptin gene C.-2548 G>A polymorphism, serum leptin levels, and body mass index in Turkish obese patients.Semantic proximity Read ↗

LEP -2548G>A Polymorphism of the Leptin Gene and Its Influence on the Lipid Profile in Obese Individuals.Semantic proximity Read ↗

Investigation of associations between obesity and LEP G2548A and LEPR 668A/G polymorphisms in a Turkish population.Semantic proximity Read ↗

Leptin gene G-2548A polymorphism in Iranian subjects with metabolic syndrome.Semantic proximity Read ↗

Leptin G-2548A promoter polymorphism is associated with increased plasma leptin and BMI in Brazilian women.Semantic proximity Read ↗

Association Between Leptin (-2548G/A) Genes Polymorphism and Breast Cancer Susceptibility: A Meta-Analysis.Semantic proximity Read ↗

Relationship Between Leptin G2548A and Leptin Receptor Q223R Gene Polymorphisms and Obesity and Metabolic Syndrome Risk in Tunisian VolunteersSemantic proximity Read ↗

Genetic Association of LEP Gene Polymorphisms with Obesity in Moroccan Individuals: Case-Control Study and Updated Meta-analysis.Semantic proximity Read ↗

[Meta-analysis on the relationship between leptin receptor Gln223Arg and Pro1019Pro gene polymorphism and obesity in the Chinese population].Semantic proximity Read ↗

-2548G>A LEP Polymorphism Is Positively Associated with Increased Leptin and Glucose Levels in Obese Saudi Patients Irrespective of Blood Pressure StatusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.