Article
LEP -2548G>A Polymorphism of the Leptin Gene and Its Influence on the Lipid Profile in Obese Individuals.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2014
Ferreira-Julio Maysa Araujo, Pinhel Marcela Souza, Quinhoneiro Driele Cristina Gomes, Nicoletti Carolina Ferreira, Brandão Antonio Carlos, Nonino Carla Barbosa, Pinheiro Sidney, Oliveira Bruno Affonso Parenti, Gregório Michele Lima, Andrade Days Oliveira, Cortes-Oliveira Cristiana, Souza Dorotéia Silva
Abstract excerpt
BACKGROUND/AIM: We studied the molecular pathogenesis of obesity, involving complex interactions between environmental and genetic factors, with a focus on the leptin gene. It was our aim to characterize the LEP -2548G>A leptin polymorphism and lipid profile in obese and normal-weight individuals. METHODS: A total of 212 individuals were divided into the study group including 136 obese patients (body mass index,...
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