Article

Generation of a Retina Reporter hiPSC Line to Label Progenitor, Ganglion, and Photoreceptor Cell Types

2019-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Early in mammalian eye development, VSX2 , BRN3b , and RCVRN expression marks neural retina progenitors (NRPs), retinal ganglion cells (RGCs), and photoreceptors (PRs), respectively. The ability to create retinal organoids from human induced pluripotent stem cells (hiPSC) holds great potential for modeling both human retinal development and retinal disease. However, no methods allowing the si...

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Literature Corpus work: e3f8cb25-24c0-5ee7-8a52-8387692ed5e0
DOI: 10.1101/658963

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