Article
Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells.
Stem cells (Dayton, Ohio) - 1 Apr 2012
Mellough Carla B, Sernagor Evelyne, Moreno-Gimeno Inmaculada, Steel David H W, Lako Majlinda
Abstract excerpt
Recent successes in the stem cell field have identified some of the key chemical and biological cues which drive photoreceptor derivation from human embryonic stem cells (hESC) and human induced pluripotent stem cells (hiPSC); however, the efficiency of this process is variable. We have designed a three-step photoreceptor differentiation protocol combining previously published methods that direct the...
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